
Publications

- Bridges to Stability: Engineering Disulfide Bonds Towards Enhanced Lipase Biodiesel Synthesis, Shalev Gihaz, Yael Bash, Inbal Rush, Dr. Anat Shahar, Dr. Yael Pazy, Prof. Ayelet Fishman, First published: 25 September 2019 https://doi.org/10.1002/cctc.201901369
- Exploiting the 1-(4-fluorobenzyl)piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural insights and biological profile. Ielo L, Deri B, Germanò MP, Vittorio S, Mirabile S, Gitto R, Rapisarda A, Ronsisvalle S, Floris S, Pazy Y, Fais A, Fishman A, De Luca L. Eur J Med Chem. 2019 Sep 15;178:380-389. doi: 10.1016/j.ejmech.2019.06.019. Epub 2019 Jun 6. PMID: 31202126
- Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Gihaz S, Kanteev M, Pazy Y, Fishman A. Appl Environ Microbiol. 2018 Nov 15;84(23):e02143-18. doi: 10.1128/AEM.02143-18. Print 2018 Dec 1. PMID: 30217852
- Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. Ferro S, Deri B, Germanò MP, Gitto R, Ielo L, Buemi MR, Certo G, Vittorio S, Rapisarda A, Pazy Y, Fishman A, De Luca L. J Med Chem. 2018 May 10;61(9):3908-3917. doi: 10.1021/acs.jmedchem.7b01745. Epub 2018 Apr 20. PMID: 29634898
- Altering 2-Hydroxybiphenyl 3-Monooxygenase Regioselectivity by Protein Engineering for the Production of a New Antioxidant. Bregman-Cohen A, Deri B, Maimon S, Pazy Y, Fishman A. Chembiochem. 2018 Mar 16;19(6):583-590. doi: 10.1002/cbic.201700648. Epub 2018 Feb 8. PMID: 29297973
- Li H, Chen Y, Ding M, Liu J, Sun H, Fang H, Brady SW, Xu Y, Glaser F, Ma X, Tang Y, Du L, Wu X, Wang S, Zhu L, Li B, Shen S, Zhang J, Zheng L, Yu J, Assaraf YG, Zhou BS. Folylpolyglutamate synthetase inactivation in relapsed ALL induces a druggable folate metabolic vulnerability. Drug Resist Updat. 2024 Aug 16;77:101141. doi: 10.1016/j.drup.2024.101141. Epub ahead of print. PMID: 39181011.
- Eliad B, Schneider N, Ben-Naim Zgayer O, Amichan Y, Glaser F, Erdmann EA, Rajendren S, Hundley HA, Lamm AT. ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection. Nucleic Acids Res. 2024 Sep 9;52(16):9501-9518. doi: 10.1093/nar/gkae641. PMID: 39036970; PMCID: PMC11381337.
- Lopens S, Schierack P, Krause J, Piaszczyński M, Król R, Staroń R, Krupa Ł, Gutkowski K, Kruk B, Grąt M, Krawczyk M, Patkowski W, Glaser F, Rödiger S, Grossmann K, Pająk J, Milkiewicz P, Lammert F, Zieniewicz K, Schramm C, Roggenbuck D, Krawczyk M. Antimicrobial glycoprotein 2 (GP2) in gallstones, bile fluid and peribiliary glands of patients with primary sclerosing cholangitis. Clin Chim Acta. 2024 Aug 15;562:119841. doi: 10.1016/j.cca.2024.119841. Epub 2024 Jul 2. PMID: 38964568.
- Eliad B, Schneider N, Zgayer OB, Amichan Y, Glaser F, Erdmann EA, Rajendren S, Hundley HA, Lamm AT. ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection. bioRxiv [Preprint]. 2024 Jun 9:2023.05.14.540679. doi: 10.1101/2023.05.14.540679. Update in: Nucleic Acids Res. 2024 Sep 9;52(16):9501-9518. doi: 10.1093/nar/gkae641. PMID: 38895382; PMCID: PMC11185548.
- Venezian J, Bar-Yosef H, Ben-Arie Zilberman H, Cohen N, Kleifeld O, Fernandez-Recio J, Glaser F, Shiber A. Diverging co-translational protein complex assembly pathways are governed by interface energy distribution. Nat Commun. 2024 Mar 25;15(1):2638. doi: 10.1038/s41467-024-46881-w. PMID: 38528060; PMCID: PMC10963368.
- Levin G, Yasmin M, Pieńko T, Yehishalom N, Hanna R, Kleifeld O, Glaser F, Schuster G. The protein phosphorylation landscape in photosystem I of the desert algae Chlorella sp. New Phytol. 2024 Apr;242(2):544-557. doi: 10.1111/nph.19603. Epub 2024 Feb 21. PMID: 38379464.
- Kocheise L, Piseddu I, Vonderlin J, Tjwa ET, Buescher G, Meunier L, Goeggelmann P, Fianchi F, Dumortier J, Barciela MR, Gevers TJG, Beretta-Piccoli BT, Londoño MC, Frankova S, Roesner T, Joerg V, Schmidt C, Glaser F, Sutter JP, Fründt TW, Lohse AW, Huber S, von Felden J, Sebode M, Schulze K. Corrigendum: PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease. Front Immunol. 2024 Jan 24;15:1369747. doi: 10.3389/fimmu.2024.1369747. Erratum for: Front Immunol. 2024 Jan 10;14:1326078. doi: 10.3389/fimmu.2023.1326078. PMID: 38327519; PMCID: PMC10848160.
- Kocheise L, Piseddu I, Vonderlin J, Tjwa ET, Buescher G, Meunier L, Goeggelmann P, Fianchi F, Dumortier J, Riveiro Barciela M, Gevers TJG, Terziroli Beretta-Piccoli B, Londoño MC, Frankova S, Roesner T, Joerg V, Schmidt C, Glaser F, Sutter JP, Fründt TW, Lohse AW, Huber S, von Felden J, Sebode M, Schulze K. PD-1/PD-L1 immune checkpoint therapy demonstrates favorable safety profile in patients with autoimmune and cholestatic liver disease. Front Immunol. 2024 Jan 10;14:1326078. doi: 10.3389/fimmu.2023.1326078. Erratum in: Front Immunol. 2024 Jan 24;15:1369747. doi: 10.3389/fimmu.2024.1369747. PMID: 38268921; PMCID: PMC10805832.
- Pandi K, Angabo S, Gnanasekaran J, Makkawi H, Eli-Berchoer L, Glaser F, Nussbaum G. Porphyromonas gingivalis induction of TLR2 association with Vinculin enables PI3K activation and immune evasion. PLoS Pathog. 2023 Apr 6;19(4):e1011284. doi: 10.1371/journal.ppat.1011284. PMID: 37023213; PMCID: PMC10112799.
- Erausquin E, Glaser F, Fernández-Recio J, López-Sagaseta J. Structural bases for the higher adherence to ACE2 conferred by the SARS-CoV-2 spike Q498Y substitution. Acta Crystallogr D Struct Biol. 2022 Sep 1;78(Pt 9):1156-1170. doi: 10.1107/S2059798322007677. Epub 2022 Aug 25. PMID: 36048155; PMCID: PMC9435600.
- Abu Hariri H, Braunstein I, Salti T, Glaser F, Gefen T, Geva-Zatorsky N, Ziv T, Benhar M. Global Thiol Proteome Analysis Provides Novel Insights into the Macrophage Inflammatory Response and Its Regulation by the Thioredoxin System. Antioxid Redox Signal. 2023 Feb;38(4-6):388-402. doi: 10.1089/ars.2022.0026. Epub 2022 Oct 18. PMID: 35979894.
- Hartl J, Rüther DF, Duengelhoef PM, Brehm TT, Steinmann S, Weltzsch JP, Glaser F, Sterneck M, Sebode M, Weiler-Normann C, Lütgehetmann M, Schaub GM, Haag F, Schramm C, Wiesch JSZ, Lohse AW. Analysis of the humoral and cellular response after the third COVID-19 vaccination in patients with autoimmune hepatitis. Liver Int. 2023 Feb;43(2):393-400. doi: 10.1111/liv.15368. Epub 2022 Aug 8. PMID: 35840342; PMCID: PMC9349728.
- Gold IM, Reis N, Glaser F, Glickman MH. Coronaviral PLpro proteases and the immunomodulatory roles of conjugated versus free Interferon Stimulated Gene product-15 (ISG15). Semin Cell Dev Biol. 2022 Dec;132:16-26. doi: 10.1016/j.semcdb.2022.06.005. Epub 2022 Jun 25. PMID: 35764457; PMCID: PMC9233553.
- Duengelhoef P, Hartl J, Rüther D, Steinmann S, Brehm TT, Weltzsch JP, Glaser F, Schaub GM, Sterneck M, Sebode M, Weiler-Normann C, Addo MM, Lütgehetmann M, Haag F, Schramm C, Schulze Zur Wiesch J, Lohse AW. SARS-CoV-2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease. United European Gastroenterol J. 2022 Apr;10(3):319-329. doi: 10.1002/ueg2.12218. Epub 2022 Mar 15. PMID: 35289983; PMCID: PMC9004241.
- Pater JA, Penney C, O'Rielly DD, Griffin A, Kamal L, Brownstein Z, Vona B, Vinkler C, Shohat M, Barel O, French CR, Singh S, Werdyani S, Burt T, Abdelfatah N, Houston J, Doucette LP, Squires J, Glaser F, Roslin NM, Vincent D, Marquis P, Woodland G, Benoukraf T, Hawkey-Noble A, Avraham KB, Stanton SG, Young TL. Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co- segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene. Hum Genet. 2022 Apr;141(3-4):431-444. doi: 10.1007/s00439-022-02444-x. Epub 2022 Mar 12. PMID: 35278131; PMCID: PMC9035003.
- Kurolap A, Kreuder F, Gonzaga-Jauregui C, Duvdevani MP, Harel T, Tammer L, Xin B, Bakhtiari S, Rice J, van Eyk CL, Gecz J, Mah JK, Atkinson D, Cope H, Sullivan JA, Douek AM, Colquhoun D, Henry J, Wlodkowic D, Parman Y, Candayan A, Kocasoy-Orhan E, Ilivitzki A, Soudry S, Leibu R, Glaser F, Sency V; Undiagnosed Diseases Network; Ast G, Shashi V, Fahey MC, Battaloğlu E, Jordanova A, Meiner V, Innes AM, Wang H, Elpeleg O, Kruer MC, Kaslin J, Baris Feldman H. Bi-allelic variants in neuronal cell adhesion molecule cause a neurodevelopmental disorder characterized by developmental delay, hypotonia, neuropathy/spasticity. Am J Hum Genet. 2022 Mar 3;109(3):518-532. doi: 10.1016/j.ajhg.2022.01.004. Epub 2022 Feb 1. PMID: 35108495; PMCID: PMC8948158.
- Pollack S, Eisenstein I, Mory A, Paperna T, Ofir A, Baris-Feldman H, Weiss K, Veszeli N, Csuka D, Shemer R, Glaser F, Prohászka Z, Magen D. A Novel Homozygous In-Frame Deletion in Complement Factor 3 Underlies Early-Onset Autosomal Recessive Atypical Hemolytic Uremic Syndrome - Case Report. Front Immunol. 2021 Jun 24;12:608604. doi: 10.3389/fimmu.2021.608604. PMID: 34248927; PMCID: PMC8264753.
- Goldmeier MN, Katz S, Glaser F, Belakhov V, Khononov A, Baasov T. Toward Catalytic Antibiotics: Redesign of Fluoroquinolones to Catalytically Fragment Chromosomal DNA. ACS Infect Dis. 2021 Mar 12;7(3):608-623. doi: 10.1021/acsinfecdis.0c00777. Epub 2021 Jan 15. PMID: 33448785.
- Harris D, Muzzopappa F, Glaser F, Wilson A, Kirilovsky D, Adir N. Structural dynamics in the C terminal domain homolog of orange carotenoid Protein reveals residues critical for carotenoid uptake. Biochim Biophys Acta Bioenerg. 2020 Aug 1;1861(8):148214. doi: 10.1016/j.bbabio.2020.148214. Epub 2020 Apr 30. PMID: 32360310.
- Russ D, Glaser F, Shaer Tamar E, Yelin I, Baym M, Kelsic ED, Zampaloni C, Haldimann A, Kishony R. Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor. Nat Commun. 2020 Apr 24;11(1):2029. doi: 10.1038/s41467-020-15666-2. PMID: 32332717; PMCID: PMC7181632.
- Lehvy AI, Horev G, Golan Y, Glaser F, Shammai Y, Assaraf YG. Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer. Cell Death Discov. 2019 Nov 12;5:144. doi: 10.1038/s41420-019-0224-0. PMID: 31728210; PMCID: PMC6851190.
- Glaser F, John C, Engel B, Höh B, Weidemann S, Dieckhoff J, Stein S, Becker N, Casar C, Schuran FA, Wieschendorf B, Preti M, Jessen F, Franke A, Carambia A, Lohse AW, Ittrich H, Herkel J, Heeren J, Schramm C, Schwinge D. Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis. J Hepatol. 2019 Oct;71(4):783-792. doi: 10.1016/j.jhep.2019.05.030. Epub 2019 Jun 14. PMID: 31207266.
- Golan Y, Alhadeff R, Glaser F, Ganoth A, Warshel A, Assaraf YG. Correction: Demonstrating aspects of multiscale modeling by studying the permeation pathway of the human ZnT2 zinc transporter. PLoS Comput Biol. 2019 May 1;15(5):e1007021. doi: 10.1371/journal.pcbi.1007021. Erratum for: PLoS Comput Biol. 2018 Nov 2;14(11):e1006503. doi: 10.1371/journal.pcbi.1006503. PMID: 31042699; PMCID: PMC6493709.
- Halpert M, Liveanu V, Glaser F, Schuster G. The Arabidopsis chloroplast RNase J displays both exo- and robust endonucleolytic activities. Plant Mol Biol. 2019 Jan;99(1-2):17-29. doi: 10.1007/s11103-018-0799-5. Epub 2018 Dec 3. PMID: 30511330.
- Golan Y, Alhadeff R, Glaser F, Ganoth A, Warshel A, Assaraf YG. Demonstrating aspects of multiscale modeling by studying the permeation pathway of the human ZnT2 zinc transporter. PLoS Comput Biol. 2018 Nov 2;14(11):e1006503. doi: 10.1371/journal.pcbi.1006503. Erratum in: PLoS Comput Biol. 2019 May 1;15(5):e1007021. doi: 10.1371/journal.pcbi.1007021. PMID: 30388104; PMCID: PMC6241132.
- Ordan M, Pallara C, Maik-Rachline G, Hanoch T, Gervasio FL, Glaser F, Fernandez-Recio J, Seger R. Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases. Sci Rep. 2018 Aug 7;8(1):11830. doi: 10.1038/s41598-018-30202-5. PMID: 30087384; PMCID: PMC6081382.
- Kurolap A, Eshach-Adiv O, Gonzaga-Jauregui C, Dolnikov K, Mory A, Paperna T, Hershkovitz T, Overton JD, Kaplan M, Glaser F, Zohar Y, Shuldiner AR, Berger G, Baris HN. Establishing the role of PLVAP in protein-losing enteropathy: a homozygous missense variant leads to an attenuated phenotype. J Med Genet. 2018 Nov;55(11):779-784. doi: 10.1136/jmedgenet-2018-105299. Epub 2018 Jun 6. PMID: 29875123.
- Yosefzon Y, Soteriou D, Feldman A, Kostic L, Koren E, Brown S, Ankawa R, Sedov E, Glaser F, Fuchs Y. Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size. Mol Cell. 2018 May 17;70(4):573-587.e4. doi: 10.1016/j.molcel.2018.04.019. PMID: 29775577.
- Yair-Sabag S, Tedeschi V, Vitulano C, Barnea E, Glaser F, Melamed Kadosh D, Taurog JD, Fiorillo MT, Sorrentino R, Admon A. The Peptide Repertoire of HLA-B27 may include Ligands with Lysine at P2 Anchor Position. Proteomics. 2018 May;18(9):e1700249. doi: 10.1002/pmic.201700249. Epub 2018 Mar 13. PMID: 29393594.
- Truman-Rosentsvit M, Berenbaum D, Spektor L, Cohen LA, Belizowsky-Moshe S, Lifshitz L, Ma J, Li W, Kesselman E, Abutbul-Ionita I, Danino D, Gutierrez L, Li H, Li K, Lou H, Regoni M, Poli M, Glaser F, Rouault TA, Meyron-Holtz EG. Ferritin is secreted via 2 distinct nonclassical vesicular pathways. Blood. 2018 Jan 18;131(3):342-352. doi: 10.1182/blood-2017-02-768580. Epub 2017 Oct 26. PMID: 29074498; PMCID: PMC5774206.
- Chojnacki M, Mansour W, Hameed DS, Singh RK, El Oualid F, Rosenzweig R, Nakasone MA, Yu Z, Glaser F, Kay LE, Fushman D, Ovaa H, Glickman MH. Polyubiquitin-Photoactivatable Crosslinking Reagents for Mapping Ubiquitin Interactome Identify Rpn1 as a Proteasome Ubiquitin-Associating Subunit. Cell Chem Biol. 2017 Apr 20;24(4):443-457.e6. doi: 10.1016/j.chembiol.2017.02.013. Epub 2017 Mar 16. PMID: 28330605; PMCID: PMC5453731.
- Schwinge D, von Haxthausen F, Quaas A, Carambia A, Otto B, Glaser F, Höh B, Thiele N, Schoknecht T, Huber S, Steffens N, Lohse AW, Herkel J, Schramm C. Dysfunction of hepatic regulatory T cells in experimental sclerosing cholangitis is related to IL-12 signaling. J Hepatol. 2017 Apr;66(4):798-805. doi: 10.1016/j.jhep.2016.12.001. Epub 2016 Dec 10. PMID: 27965154.
- Romero-Durana M, Pallara C, Glaser F, Fernández-Recio J. Modeling Binding Affinity of Pathological Mutations for Computational Protein Design. Methods Mol Biol. 2017;1529:139-159. doi: 10.1007/978-1-4939-6637-0_6. PMID: 27914049.
- Corrochano LM, Kuo A, Marcet-Houben M, Polaino S, Salamov A, Villalobos- Escobedo JM, Grimwood J, Álvarez MI, Avalos J, Bauer D, Benito EP, Benoit I, Burger G, Camino LP, Cánovas D, Cerdá-Olmedo E, Cheng JF, Domínguez A, Eliáš M, Eslava AP, Glaser F, Gutiérrez G, Heitman J, Henrissat B, Iturriaga EA, Lang BF, Lavín JL, Lee SC, Li W, Lindquist E, López-García S, Luque EM, Marcos AT, Martin J, McCluskey K, Medina HR, Miralles-Durán A, Miyazaki A, Muñoz-Torres E, Oguiza JA, Ohm RA, Olmedo M, Orejas M, Ortiz-Castellanos L, Pisabarro AG, Rodríguez- Romero J, Ruiz-Herrera J, Ruiz-Vázquez R, Sanz C, Schackwitz W, Shahriari M, Shelest E, Silva-Franco F, Soanes D, Syed K, Tagua VG, Talbot NJ, Thon MR, Tice H, de Vries RP, Wiebenga A, Yadav JS, Braun EL, Baker SE, Garre V, Schmutz J, Horwitz BA, Torres-Martínez S, Idnurm A, Herrera-Estrella A, Gabaldón T, Grigoriev IV. Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication. Curr Biol. 2016 Jun 20;26(12):1577-1584. doi: 10.1016/j.cub.2016.04.038. Epub 2016 May 26. PMID: 27238284; PMCID: PMC5089372.
- Golan Y, Itsumura N, Glaser F, Berman B, Kambe T, Assaraf YG. Molecular Basis of Transient Neonatal Zinc Deficiency: NOVEL ZnT2 MUTATIONS DISRUPTING ZINC BINDING AND PERMEATION. J Biol Chem. 2016 Jun 24;291(26):13546-59. doi: 10.1074/jbc.M116.732693. Epub 2016 May 2. PMID: 27137936; PMCID: PMC4919441.
- Hosseini A, Brouk M, Lucas MF, Glaser F, Fishman A, Guallar V. Atomic picture of ligand migration in toluene 4-monooxygenase. J Phys Chem B. 2015 Jan 22;119(3):671-8. doi: 10.1021/jp502509a. Epub 2014 May 13. PMID: 24798294.
- Lasry I, Golan Y, Berman B, Amram N, Glaser F, Assaraf YG. In situ dimerization of multiple wild type and mutant zinc transporters in live cells using bimolecular fluorescence complementation. J Biol Chem. 2014 Mar 14;289(11):7275-92. doi: 10.1074/jbc.M113.533786. Epub 2014 Jan 22. PMID: 24451381; PMCID: PMC3953246.
- Behar DM, Basel-Vanagaite L, Glaser F, Kaplan M, Tzur S, Magal N, Eidlitz- Markus T, Haimi-Cohen Y, Sarig G, Bormans C, Shohat M, Zeharia A. Identification of a novel mutation in the PNLIP gene in two brothers with congenital pancreatic lipase deficiency. J Lipid Res. 2014 Feb;55(2):307-12. doi: 10.1194/jlr.P041103. Epub 2013 Nov 21. PMID: 24262094; PMCID: PMC3886669.
- Pérez-Cano L, Eliahoo E, Lasker K, Wolfson HJ, Glaser F, Manor H, Bernadó P, Fernández-Recio J. Conformational transitions in human translin enable nucleic acid binding. Nucleic Acids Res. 2013 Nov;41(21):9956-66. doi: 10.1093/nar/gkt765. Epub 2013 Aug 26. PMID: 23980029; PMCID: PMC3834833.
- Gupta SK, Kosti I, Plaut G, Pivko A, Tkacz ID, Cohen-Chalamish S, Biswas DK, Wachtel C, Waldman Ben-Asher H, Carmi S, Glaser F, Mandel-Gutfreund Y, Michaeli S. The hnRNP F/H homologue of Trypanosoma brucei is differentially expressed in the two life cycle stages of the parasite and regulates splicing and mRNA stability. Nucleic Acids Res. 2013 Jul;41(13):6577-94. doi: 10.1093/nar/gkt369. Epub 2013 May 10. PMID: 23666624; PMCID: PMC3711420.
- Shainsky J, Bernath-Levin K, Isaschar-Ovdat S, Glaser F, Fishman A. Protein engineering of nirobenzene dioxygenase for enantioselective synthesis of chiral sulfoxides. Protein Eng Des Sel. 2013 May;26(5):335-45. doi: 10.1093/protein/gzt005. Epub 2013 Feb 26. PMID: 23442445.
- Cohen-Katsenelson K, Wasserman T, Darlyuk-Saadon I, Rabner A, Glaser F, Aronheim A. Identification and analysis of a novel dimerization domain shared by various members of c-Jun N-terminal kinase (JNK) scaffold proteins. J Biol Chem. 2013 Mar 8;288(10):7294-304. doi: 10.1074/jbc.M112.422055. Epub 2013 Jan 22. PMID: 23341463; PMCID: PMC3591637.
- Ohm RA, Feau N, Henrissat B, Schoch CL, Horwitz BA, Barry KW, Condon BJ, Copeland AC, Dhillon B, Glaser F, Hesse CN, Kosti I, LaButti K, Lindquist EA, Lucas S, Salamov AA, Bradshaw RE, Ciuffetti L, Hamelin RC, Kema GH, Lawrence C, Scott JA, Spatafora JW, Turgeon BG, de Wit PJ, Zhong S, Goodwin SB, Grigoriev IV. Diverse lifestyles and strategies of plant pathogenesis encoded in the genomes of eighteen Dothideomycetes fungi. PLoS Pathog. 2012;8(12):e1003037. doi: 10.1371/journal.ppat.1003037. Epub 2012 Dec 6. PMID: 23236275; PMCID: PMC3516569.
- Eshar S, Allemand E, Sebag A, Glaser F, Muchardt C, Mandel-Gutfreund Y, Karni R, Dzikowski R. A novel Plasmodium falciparum SR protein is an alternative splicing factor required for the parasites' proliferation in human erythrocytes. Nucleic Acids Res. 2012 Oct;40(19):9903-16. doi: 10.1093/nar/gks735. Epub 2012 Aug 9. PMID: 22885299; PMCID: PMC3479193.
- Lasry I, Seo YA, Ityel H, Shalva N, Pode-Shakked B, Glaser F, Berman B, Berezovsky I, Goncearenco A, Klar A, Levy J, Anikster Y, Kelleher SL, Assaraf YG. A dominant negative heterozygous G87R mutation in the zinc transporter, ZnT-2 (SLC30A2), results in transient neonatal zinc deficiency. J Biol Chem. 2012 Aug 24;287(35):29348-61. doi: 10.1074/jbc.M112.368159. Epub 2012 Jun 25. PMID: 22733820; PMCID: PMC3436150.
- Atamna-Ismaeel N, Finkel O, Glaser F, von Mering C, Vorholt JA, Koblížek M, Belkin S, Béjà O. Bacterial anoxygenic photosynthesis on plant leaf surfaces. Environ Microbiol Rep. 2012 Apr;4(2):209-16. doi: 10.1111/j.1758-2229.2011.00323.x. Epub 2012 Jan 16. PMID: 23757275.
- Béjà O, Fridman S, Glaser F. Viral clones from the GOS expedition with an unusual photosystem-I gene cassette organization. ISME J. 2012 Aug;6(8):1617-20. doi: 10.1038/ismej.2012.23. Epub 2012 Mar 29. PMID: 22456446; PMCID: PMC3400403.
- Pevzner I, Strating J, Lifshitz L, Parnis A, Glaser F, Herrmann A, Brügger B, Wieland F, Cassel D. Distinct role of subcomplexes of the COPI coat in the regulation of ArfGAP2 activity. Traffic. 2012 Jun;13(6):849-56. doi: 10.1111/j.1600-0854.2012.01349.x. Epub 2012 Mar 28. PMID: 22375848.
- Dror I, Shazman S, Mukherjee S, Zhang Y, Glaser F, Mandel-Gutfreund Y. Predicting nucleic acid binding interfaces from structural models of proteins. Proteins. 2012 Feb;80(2):482-9. doi: 10.1002/prot.23214. Epub 2011 Nov 16. PMID: 22086767; PMCID: PMC3290761.
- Feingersch R, Philosof A, Mejuch T, Glaser F, Alalouf O, Shoham Y, Béjà O. Potential for phosphite and phosphonate utilization by Prochlorococcus. ISME J. 2012 Apr;6(4):827-34. doi: 10.1038/ismej.2011.149. Epub 2011 Oct 20. PMID: 22011717; PMCID: PMC3309357.
- Pons C, Glaser F, Fernandez-Recio J. Prediction of protein-binding areas by small-world residue networks and application to docking. BMC Bioinformatics. 2011 Sep 26;12:378. doi: 10.1186/1471-2105-12-378. PMID: 21943333; PMCID: PMC3189935.
- Atamna-Ismaeel N, Finkel OM, Glaser F, Sharon I, Schneider R, Post AF, Spudich JL, von Mering C, Vorholt JA, Iluz D, Béjà O, Belkin S. Microbial rhodopsins on leaf surfaces of terrestrial plants. Environ Microbiol. 2012 Jan;14(1):140-6. doi: 10.1111/j.1462-2920.2011.02554.x. Epub 2011 Sep 1. PMID: 21883799; PMCID: PMC3608849.
- Malik A, Korol A, Hübner S, Hernandez AG, Thimmapuram J, Ali S, Glaser F, Paz A, Avivi A, Band M. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. PLoS One. 2011;6(8):e21227. doi: 10.1371/journal.pone.0021227. Epub 2011 Aug 12. PMID: 21857902; PMCID: PMC3155515.
- Bornstein B, Gottfried Y, Edison N, Shekhtman A, Lev T, Glaser F, Larisch S. ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists. Apoptosis. 2011 Sep;16(9):869-81. doi: 10.1007/s10495-011-0622-0. PMID: 21695558.
- Rosenfeld KK, Ziv T, Goldin S, Glaser F, Manor H. Mapping of DNA binding sites in the Tetrahymena telomerase holoenzyme proteins by UV cross-linking and mass spectrometry. J Mol Biol. 2011 Jul 1;410(1):77-92. doi: 10.1016/j.jmb.2011.04.040. Epub 2011 Apr 27. PMID: 21549126.
- Kubicek CP, Herrera-Estrella A, Seidl-Seiboth V, Martinez DA, Druzhinina IS, Thon M, Zeilinger S, Casas-Flores S, Horwitz BA, Mukherjee PK, Mukherjee M, Kredics L, Alcaraz LD, Aerts A, Antal Z, Atanasova L, Cervantes-Badillo MG, Challacombe J, Chertkov O, McCluskey K, Coulpier F, Deshpande N, von Döhren H, Ebbole DJ, Esquivel-Naranjo EU, Fekete E, Flipphi M, Glaser F, Gómez-Rodríguez EY, Gruber S, Han C, Henrissat B, Hermosa R, Hernández-Oñate M, Karaffa L, Kosti I, Le Crom S, Lindquist E, Lucas S, Lübeck M, Lübeck PS, Margeot A, Metz B, Misra M, Nevalainen H, Omann M, Packer N, Perrone G, Uresti-Rivera EE, Salamov A, Schmoll M, Seiboth B, Shapiro H, Sukno S, Tamayo-Ramos JA, Tisch D, Wiest A, Wilkinson HH, Zhang M, Coutinho PM, Kenerley CM, Monte E, Baker SE, Grigoriev IV. Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma. Genome Biol. 2011;12(4):R40. doi: 10.1186/gb-2011-12-4-r40. Epub 2011 Apr 18. PMID: 21501500; PMCID: PMC3218866.
- Sharon I, Battchikova N, Aro EM, Giglione C, Meinnel T, Glaser F, Pinter RY, Breitbart M, Rohwer F, Béjà O. Comparative metagenomics of microbial traits within oceanic viral communities. ISME J. 2011 Jul;5(7):1178-90. doi: 10.1038/ismej.2011.2. Epub 2011 Feb 10. PMID: 21307954; PMCID: PMC3146289.
- Inbar E, Canepa GE, Carrillo C, Glaser F, Suter Grotemeyer M, Rentsch D, Zilberstein D, Pereira CA. Lysine transporters in human trypanosomatid pathogens. Amino Acids. 2012 Jan;42(1):347-60. doi: 10.1007/s00726-010-0812-z. Epub 2010 Dec 18. PMID: 21170560.
- Alperovitch-Lavy A, Sharon I, Rohwer F, Aro EM, Glaser F, Milo R, Nelson N, Béjà O. Reconstructing a puzzle: existence of cyanophages containing both photosystem-I and photosystem-II gene suites inferred from oceanic metagenomic datasets. Environ Microbiol. 2011 Jan;13(1):24-32. doi: 10.1111/j.1462-2920.2010.02304.x. PMID: 20649642.
- Kosti I, Mandel-Gutfreund Y, Glaser F, Horwitz BA. Comparative analysis of fungal protein kinases and associated domains. BMC Genomics. 2010 Feb 24;11:133. doi: 10.1186/1471-2164-11-133. PMID: 20178650; PMCID: PMC2838846.
- Eliahoo E, Ben Yosef R, Pérez-Cano L, Fernández-Recio J, Glaser F, Manor H. Mapping of interaction sites of the Schizosaccharomyces pombe protein Translin with nucleic acids and proteins: a combined molecular genetics and bioinformatics study. Nucleic Acids Res. 2010 May;38(9):2975-89. doi: 10.1093/nar/gkp1230. Epub 2010 Jan 15. PMID: 20081200; PMCID: PMC2875027.
- Sharon I, Alperovitch A, Rohwer F, Haynes M, Glaser F, Atamna-Ismaeel N, Pinter RY, Partensky F, Koonin EV, Wolf YI, Nelson N, Béjà O. Photosystem I gene cassettes are present in marine virus genomes. Nature. 2009 Sep 10;461(7261):258-262. doi: 10.1038/nature08284. Epub 2009 Aug 26. PMID: 19710652; PMCID: PMC4605144.
- Lasry I, Berman B, Glaser F, Jansen G, Assaraf YG. Hereditary folate malabsorption: a positively charged amino acid at position 113 of the proton- coupled folate transporter (PCFT/SLC46A1) is required for folic acid binding. Biochem Biophys Res Commun. 2009 Aug 28;386(3):426-31. doi: 10.1016/j.bbrc.2009.06.007. Epub 2009 Jun 7. PMID: 19508863.
- Aviram S, Simon E, Gildor T, Glaser F, Kornitzer D. Autophosphorylation- induced degradation of the Pho85 cyclin Pcl5 is essential for response to amino acid limitation. Mol Cell Biol. 2008 Nov;28(22):6858-69. doi: 10.1128/MCB.00367-08. Epub 2008 Sep 15. PMID: 18794371; PMCID: PMC2573309.
- Lasry I, Berman B, Straussberg R, Sofer Y, Bessler H, Sharkia M, Glaser F, Jansen G, Drori S, Assaraf YG. A novel loss-of-function mutation in the proton- coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function. Blood. 2008 Sep 1;112(5):2055-61. doi: 10.1182/blood-2008-04-150276. Epub 2008 Jun 17. PMID: 18559978.
- Schein A, Sheffy-Levin S, Glaser F, Schuster G. The RNase E/G-type endoribonuclease of higher plants is located in the chloroplast and cleaves RNA similarly to the E. coli enzyme. RNA. 2008 Jun;14(6):1057-68. doi: 10.1261/rna.907608. Epub 2008 Apr 25. PMID: 18441049; PMCID: PMC2390796.
- Portnoy V, Palnizky G, Yehudai-Resheff S, Glaser F, Schuster G. Analysis of the human polynucleotide phosphorylase (PNPase) reveals differences in RNA binding and response to phosphate compared to its bacterial and chloroplast counterparts. RNA. 2008 Feb;14(2):297-309. doi: 10.1261/rna.698108. Epub 2007 Dec 14. PMID: 18083836; PMCID: PMC2212259.
- Favia AD, Nobeli I, Glaser F, Thornton JM. Molecular docking for substrate identification: the short-chain dehydrogenases/reductases. J Mol Biol. 2008 Jan 18;375(3):855-74. doi: 10.1016/j.jmb.2007.10.065. Epub 2007 Nov 1. PMID: 18036612.
- Shazman S, Celniker G, Haber O, Glaser F, Mandel-Gutfreund Y. Patch Finder Plus (PFplus): a web server for extracting and displaying positive electrostatic patches on protein surfaces. Nucleic Acids Res. 2007 Jul;35(Web Server issue):W526-30. doi: 10.1093/nar/gkm401. Epub 2007 May 30. PMID: 17537808; PMCID: PMC1933175.
- Glaser F, Morris RJ, Najmanovich RJ, Laskowski RA, Thornton JM. A method for localizing ligand binding pockets in protein structures. Proteins. 2006 Feb 1;62(2):479-88. doi: 10.1002/prot.20769. PMID: 16304646.
- Furmonaviciene R, Sutton BJ, Glaser F, Laughton CA, Jones N, Sewell HF, Shakib F. An attempt to define allergen-specific molecular surface features: a bioinformatic approach. Bioinformatics. 2005 Dec 1;21(23):4201-4. doi: 10.1093/bioinformatics/bti700. Epub 2005 Oct 4. PMID: 16204345.
- Landau M, Mayrose I, Rosenberg Y, Glaser F, Martz E, Pupko T, Ben-Tal N. ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W299-302. doi: 10.1093/nar/gki370. PMID: 15980475; PMCID: PMC1160131.
- Nimrod G, Glaser F, Steinberg D, Ben-Tal N, Pupko T. In silico identification of functional regions in proteins. Bioinformatics. 2005 Jun;21 Suppl 1:i328-37. doi: 10.1093/bioinformatics/bti1023. PMID: 15961475.
- Glaser F, Rosenberg Y, Kessel A, Pupko T, Ben-Tal N. The ConSurf-HSSP database: the mapping of evolutionary conservation among homologs onto PDB structures. Proteins. 2005 Feb 15;58(3):610-7. doi: 10.1002/prot.20305. PMID: 15614759.
- Melamed D, Mark-Danieli M, Kenan-Eichler M, Kraus O, Castiel A, Laham N, Pupko T, Glaser F, Ben-Tal N, Bacharach E. The conserved carboxy terminus of the capsid domain of human immunodeficiency virus type 1 gag protein is important for virion assembly and release. J Virol. 2004 Sep;78(18):9675-88. doi: 10.1128/JVI.78.18.9675-9688.2004. PMID: 15331700; PMCID: PMC514996.
- Berezin C, Glaser F, Rosenberg J, Paz I, Pupko T, Fariselli P, Casadio R, Ben-Tal N. ConSeq: the identification of functionally and structurally important residues in protein sequences. Bioinformatics. 2004 May 22;20(8):1322-4. doi: 10.1093/bioinformatics/bth070. Epub 2004 Feb 10. PMID: 14871869.
- Glaser F, Pupko T, Paz I, Bell RE, Bechor-Shental D, Martz E, Ben-Tal N. ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information. Bioinformatics. 2003 Jan;19(1):163-4. doi: 10.1093/bioinformatics/19.1.163. PMID: 12499312.
- Pupko T, Bell RE, Mayrose I, Glaser F, Ben-Tal N. Rate4Site: an algorithmic tool for the identification of functional regions in proteins by surface mapping of evolutionary determinants within their homologues. Bioinformatics. 2002;18 Suppl 1:S71-7. doi: 10.1093/bioinformatics/18.suppl_1.s71. PMID: 12169533.
- Gottfried I, Landau M, Glaser F, Di WL, Ophir J, Mevorah B, Ben-Tal N, Kelsell DP, Avraham KB. A mutation in GJB3 is associated with recessive erythrokeratodermia variabilis (EKV) and leads to defective trafficking of the connexin 31 protein. Hum Mol Genet. 2002 May 15;11(11):1311-6. doi: 10.1093/hmg/11.11.1311. PMID: 12019212.
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